Testosterone-Enanthate: Product Description
Testosterone enanthate is an injectable testosterone supplement commonly used to treat low testosterone and symptoms of hypogonadism in males. This slow-release oil-based ester can be administered either intramuscularly or subcutaneously, depending on the healthcare provider’s preference or the individual’s needs. Clinically, it was first used to treat low testosterone in 1937, and its popularity among men has significantly increased since then.
Dosage Strength:
Testosterone Enanthate Injection (Grapeseed Oil) (5 mL Vial)
Testosterone Enanthate Injection (Grapeseed Oil) (10 mL Vial)
Testosterone Enanthate Injection (5 mL Vial)
Mechanism of Action
Testosterone exerts its effects in the body primarily by binding to and interacting with androgen receptors. Once secreted by the testes, testosterone can be converted into a more potent metabolite known as dihydrotestosterone (DHT). This conversion is facilitated by the enzyme 5-alpha reductase, which operates in the cytoplasm of target tissues.
Formation of DHT-Receptor Complex
DHT binds to androgen receptors inside the cytoplasm of target cells, forming a DHT-receptor complex. This complex then translocates into the nucleus of the cells, where it binds to specific nucleotide sequences on the chromosomal DNA. This binding initiates nuclear transcription, resulting in the synthesis of proteins that carry out various biological functions.
Contraindications and Cautions for Testosterone Injections
Testosterone injections should be avoided or administered with caution under the following circumstances:
- Cancer History: Testosterone is contraindicated in men with any form of breast or prostate cancer.
- Hypersensitivity: Individuals who are hypersensitive to any components of testosterone enanthate should not receive these injections.
- Pregnancy: Women who are pregnant or have a high likelihood of becoming pregnant should avoid testosterone injections, as they may lead to the masculinization of the fetus.
- Impaired Organ Function: Caution is warranted when administering testosterone to individuals with impaired liver or kidney function.
Potential Side Effects of Testosterone Enanthate Injections
Exogenous administration of testosterone enanthate injections may lead to several side effects, including:
- Liver Conditions: Possible liver complications such as peliosis hepatitis and hepatocellular carcinoma.
- Prostate Issues: Elderly males may experience prostate enlargement and an increased risk of prostatic carcinoma.
- Cardiovascular Concerns: Individuals with pre-existing cardiovascular conditions may experience swelling in the lower limbs due to salt and water retention.
- Gynecomastia: Some men may develop enlarged breasts, a condition known as gynecomastia.
Refills
Testosterone is a controlled substance and can be refilled 3-7 days prior to due date. Automated reminders will be sent for refill dates.
Disclaimer
This document is for informational purposes only and is not a substitute for professional medical advice. Always consult your healthcare provider for guidance specific to your health and medication needs. Follow your provider’s instructions and report any side effects or concerns immediately.
