Product Description
SARMs MK677- Ibutamoren, better known by researchers as MK 677 or nutrobal is a human growth hormone secretagogue. According to current research, MK 677 engages with the pituitary gland to promote the secretion of HGH. In addition to its ability to release HGH, research found that MK-677 can also slow the release of somatostatin, a hormone tasked with the regulation of human growth hormone.
SARMs are not evaluated by the FDA, nor are they allowed by WADA.
| Application : | High-affinity ghrelin receptor agonist |
| CAS: | 159752-10-0 |
| Molecular Weight: | 528.662 g/mol |
| Chemical Formula: | C27H36N4O5S.CH3SO3H |
| Chemical Name: | (R)-1′-(2-methylalanyl-O-benzyl-D-seryl)-1-(methylsulfonyl)-1,2-dihydrospiro[indole-3,4′-piperidine] |
| Synonyms: | Ibutamoren, MK-677, MK-0677, L-163,191, L163191, Nutrobal |
| Storage: | Minimize open-air exposure, and store in a cool dry place |
| Stability: | 2 years |
| Purity: | 99% |
| Solubility: | Soluble to 50 mM in water |
| Organoleptic Profile: | Off-white to beige fine powder, hygroscopic, acrid odor, acrid metallic taste |
| Physical Form: | A crystalline solid |
| Specifications: | 12.5mg/capsule |
| Container: | 60 MK677 (Ibutamoren) capsules |
| Terms: | The products we offer are intended for laboratory research use only. |
SARMs are compounds that are currently being studied as a possible replacement for anabolic agents, unlike anabolic steroids that have serious side effects, these compounds have very few side effects in general.
Ibutamoren MK-677 works by attaching itself to ghrelin receptors. By doing so, there may be a stimulation resulting in higher GH and IGF-1 levels.
Ibutamoren MK-677 is a potent growth hormone secretagogue that functions by selectively binding to ghrelin receptors. This mechanism stimulates the endogenous secretion of growth hormone (GH) and insulin-like growth factor 1 (IGF-1), both of which are crucial for various metabolic processes and overall health.
Ibutamoren MK-677 works by attaching itself to ghrelin receptors. By doing so, there may be a stimulation resulting in higher GH and IGF-1 levels.
Sleep Studies
Recent studies have investigated the efficacy of MK-677 in improving sleep quality. One such study involved two groups: younger subjects aged 18 to 30 and older individuals aged 65 to 71. Over three treatment phases lasting seven days each, participants received either a placebo or MK-677. Results indicated that MK-677 significantly improved sleep quality in both age groups and effectively addressed age-related hyposomatotropism, a condition characterized by decreased GH levels.
Additional Clinical Trials
- Younger Males (Aged 19-49): An eight-week study evaluated MK-677’s impact on GH secretion, body composition, and energy levels. Participants exhibited an anabolic response, characterized by a sustained increase in fat-free mass and a temporary elevation in basal metabolic rate. This suggests that MK-677 may be beneficial for those aiming to improve body composition and athletic performance.
- Older Adults (Aged 60-81): A double-blind, two-year study assessed the effects of daily MK-677 administration on body composition and visceral fat. Findings revealed significant increases in both GH and IGF-1, along with notable improvements in fat-free mass and bone remodeling, indicating potential benefits for aging populations.
Potential Benefits of MK-677
- Increased Lean Muscle Mass: By elevating GH and IGF-1 levels, MK-677 promotes muscle hypertrophy and strength gains.
- Enhanced Appetite: As a ghrelin mimic, MK-677 may stimulate appetite, beneficial for individuals looking to gain weight or muscle.
- Cognitive Improvement: Preliminary studies suggest that increased GH and IGF-1 may enhance memory and cognitive function.
- Restorative Sleep: MK-677 has demonstrated the ability to promote restful sleep, addressing common sleep disturbances.
- Mood and Metabolic Enhancement: Users report improved mood, metabolism, and libido, contributing to an overall sense of well-being.
